Wine and health is an issue of considerable discussion and research. Wine has a long history of use as an early form of medication, being recommended variously as a safe alternative to drinking water, an antiseptic for treating wounds, a digestive aid, and as a cure for a wide range of ailments including lethargy, diarrhea and pain from child birth. Ancient Egyptian Papyri and Sumerian tablets dating back to 2200 BC detail the medicinal role of wine, making it the world’s oldest documented man-made medicine. Wine continued to play a major role in medicine until the late 19th and early 20th century, when changing opinions and medical research on alcohol and alcoholism cast doubt on its role as part of a healthy lifestyle. In the late 20th and early 21st century, fueled in part by public interest in reports by the United States news broadcast 60 Minutes on the so-called “French Paradox”, the medical establishment began to re-evaluate the role of moderate wine consumption in health.